Trephina Gorge is a gorge in the Northern Territory of Australia located in the locality of Hart in the East MacDonnell Ranges about 85 kilometres east of Alice Springs. The gorge is named after the Trephina Creek which is believed to be named after Tryphina Benstead who was the wife of William Benstead, the manager of Undoolya Station from 1877 onwards and the first licensee of the Stuart Arms Hotel in Alice Springs.