Kirksville Regional Airport is four miles south of Kirksville, Missouri, on the west side of US highway 63. One airline schedules passenger flights, subsidized by the Essential Air Service program. Federal Aviation Administration records say the airport had 684 passenger boardings in calendar year 2008, 926 in 2009 and 2,127 in 2010. The National Plan of Integrated Airport Systems for 2011–2015 categorized it as a general aviation facility.