Founded and still headquartered in Rose Hill, N.C., Duplin Winery is the largest winery in the South and listed as the nation’s 39th Largest Winery by Wine Business Monthly magazine. Specializing in wines made from America’s native muscadine grapes, Duplin is the largest muscadine winery in the world with a tank capacity of more than 2.3 million gallons. Duplin operates locations in Rose Hill, NC North Myrtle Beach, SC and Panama City Beach, FL.