The New York Hilton Midtown is the largest hotel in New York City and world's 101st tallest hotel. The hotel is corporate owned and managed by Hilton Inc. At 1,980 rooms and over 150,000 sq ft of meeting space, the hotel is the largest Hilton in the continental U.S. The 47-floor building located on the northwest edge of Rockefeller Center at Sixth Avenue and 53rd Street has hosted every U.S. president since John F.