Baylis House is a Grade I listed building currently operating as a hotel and business centre in Slough, Berkshire, England. It is representative of the plain Dutch style that was popular in England after post-Civil war restoration of the English monarchy in 1660. Little is known of the original building that stood on the site of the current house. In the 16th century it was recorded as the 'manor of Bailis'. It formed part of the estate of Abraham Sybells's at his death in 1501.
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