The Wilson-Gibson House is a historic residence in Cincinnati, Ohio, United States. Constructed in the middle of the 19th century, it features a mix of two prominent architectural styles, and it has been named a historic site. The lot currently located at 425 Oak Street was originally part of a subdivision known as "Vernon Village". Although the property was first owned by John Frazier, James Wilson bought it in 1859 at sheriff's sale and soon began construction on the site.