Mission San Carlos Borromeo del río Carmelo, also known as the Carmel Mission or Mission Carmel, is a Roman Catholic mission church in Carmel-by-the-Sea, California. It is on the National Register of Historic Places and a U.S. National Historic Landmark. The mission was the headquarters of the Alta California missions headed by Saint Junípero Serra from 1770 until his death in 1784. It was also the seat of the second presidente, Father Fermin Francisco de Lasuen.