Rex Hospital is a general hospital located in Raleigh, North Carolina. It is the capital city's oldest hospital, founded by a bequest from John T Rex (1771-1839), a tanner and respected member of the local society. Originally located on what is now Dorothea Dix campus, and later on St. Mary's Street, Rex is now located in west Raleigh at the corner of Blue Ridge Road and Lake Boone Trail.