Manchester Piccadilly is the principal railway station in Manchester, England. Opened as Store Street in 1842, it was renamed Manchester London Road in 1847 and Manchester Piccadilly in 1960. It hosts intercity and cross-country services to national destinations including London Euston, Birmingham, Bristol, Bournemouth, South Wales and Scotland, and local and regional services to destinations in Northern England including Liverpool, Leeds, Sheffield, Newcastle and York.