Payne-Gentry House is a historic one story, red brick, vernacular-style cottage home located in Bridgeton, St. Louis County, Missouri. It was built in 1870. The Payne-Gentry house contains the only surviving historic Missouri house with a restored doctor’s office from the 19th century period. The house has six entrances and a gable roof. The house was added to the National Register of Historic Places in 1979.