The Monastery of St. Jerome is a Roman Catholic church and Hieronymite monastery in Granada, Spain. Architecturally, it is in the Renaissance style. The church was the first in the world consecrated to the Immaculate Conception of Mary. The monastery was founded by the Catholic Monarchs Isabella I of Castile and Ferdinand II of Aragon in Santa Fe outside the city of Granada, during the siege of the latter city, the last stage of the Reconquista.