Murano Grande at Portofino is a residential enclave tower /skyscraper in Miami Beach, Florida's South Beach. It is located directly on Biscayne Bay on the Miami Beach Marina. The tower, which opened in 2003, is 407 ft (124 m) tall and contains 37 floors. It is located in the exclusive "SOFI"(South of Fifth Street) neighborhood. It contains some of the most luxurious as well as some of the largest units in the area.