Wandsbek is the second-largest of seven boroughs that make up the city and state of Hamburg, Germany. The name of the district is derived from the river Wandse which passes through here. Wandsbek, which was formerly an independent city, is urban and, along with Eilbek and Marienthal, part of the city's economic and cultural core. In 2020 the population was 442,702, making it the most populous borough in Hamburg.