Plasencia is a municipality of Spain belonging to the province of Cáceres, Extremadura. As of 2013, it has a population of 41,047. Plasencia is located in the Western-Central Iberian Peninsula, to the south of the Sistema Central. Housing primarily lies on the right bank of the Jerte. Plasencia is part of the so-called Ruta de la Plata, a north-south commercial path across Western Spain.