Preston is an unincorporated community located in Okmulgee County, Oklahoma, United States. The population was 169 at the 2020 census. The post office was established December 13, 1909. It was named for an Okmulgee oilman, Harry Preston. First known as Hamilton Switch, and now unrecognizable from the past, Preston was once a highly prosperous community, thriving mainly from the oil boom, as did many of the surrounding communities.