Point Lookout is a hamlet and census-designated place located in the town of Hempstead in Nassau County, New York, United States. The population was 1,527 at the time of the 2020 census. The town is mostly made up of residential homes, with several small businesses on Lido Boulevard. The town is surrounded on three sides by water. Today, Point Lookout has become a popular location for summer residences. Among its inhabitants, it is commonly referred to as "PLO".