Palosco is a comune in the Province of Bergamo in the Italian region of Lombardy, located about 50 kilometres east of Milan and about 20 kilometres southeast of Bergamo. As of 31 December 2004, it had a population of 5,353 and an area of 10.4 square kilometres. Palosco borders the following municipalities: Bolgare, Calcinate, Cividate al Piano, Martinengo, Mornico al Serio, Palazzolo sull'Oglio, Pontoglio, Telgate.