South Penrith is a suburb of Sydney, in the state of New South Wales, Australia. South Penrith is located 55 kilometres west of the Sydney central business district, in the local government area of the City of Penrith and is part of the Greater Western Sydney region. South Penrith is bounded by Jamison Road to the north, York Road to the west, the M4 Motorway to the south and the Northern Road to the east. Penrith is a separate suburb to the north.