East Palo Alto (abbreviated E.P.A.) is a city in San Mateo County, California, United States. As of the 2010 census, the population of East Palo Alto was 28,155. It is situated on the San Francisco Peninsula, roughly halfway between the cities of San Francisco and San Jose. To the north and east is the San Francisco Bay, to the west is the city of Menlo Park, and to the south the city of Palo Alto.