St. Lorenzen is a comune in South Tyrol in northern Italy, located about 50 kilometers northeast of Bolzano. As of 30 November 2010, it had a population of 3,752 and an area of 51.5 km2. St Lorenzen borders the following municipalities: Bruneck, Kiens, Pfalzen, Lüsen, Mareo, and Rodeneck.