Seneca Rocks is an unincorporated community located in Pendleton County, West Virginia, United States. The community of Seneca Rocks — formerly known as Mouth of Seneca — lies at the junction of US 33, WV 28 and WV 55 near the confluence of Seneca Creek and the North Fork South Branch Potomac River. The community also lies near Seneca Rocks, the crag from which it takes its name. Both lie within the Spruce Knob–Seneca Rocks National Recreation Area of the Monongahela National Forest.