Civitella Paganico is a comune in the Province of Grosseto in the Italian region Tuscany. It features agricultural land, the main economy of the region, interspersed with dense forest. It is home to a variety of plant and animal species. Civitella Paganico is home to the Petriolo hot springs, which have been enjoyed by travelers for thousands of years. Civilization in Civitella Paganico likely dates back to the Palaeolithic age. It is home to Etruscan and Roman remains.