Hancock County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 29,095. Its county seat is New Cumberland and its largest city is Weirton. The county was created from Brooke County in 1848 and named for John Hancock, first signer of the Declaration of Independence. Located at the tip of the state's Northern Panhandle, Hancock County is the northernmost point in both West Virginia and, by some definitions, the Southern United States.