Lane County is one of the 36 counties in the U.S. state of Oregon. As of the 2020 census, the population was 382,971, making it the fourth-most populous county in Oregon. The county seat is Eugene, the state's second most populous city. It is named in honor of Joseph Lane, Oregon's first territorial governor. Lane County comprises the Eugene, OR Metropolitan Statistical Area. It is the third-largest MSA in Oregon, and the 144th-largest in the country.