Winesburg is an unincorporated community and census-designated place in Paint Township, Holmes County, Ohio, in the United States. The population was 340 at the 2020 census. The community sits on the crest of a hill in the Amish country of Ohio. It lies along U.S. Route 62. It is not the setting of the novel Winesburg, Ohio by Sherwood Anderson, a collection of inter-related fictional short stories about citizens of a small town set in the early 20th century.