Duson is a town in Acadia and Lafayette parishes in the U.S. state of Louisiana. The town was named after Curley Duson, a sheriff of St. Landry Parish. At the 2010 U.S. census, the town had a population of 1,716; in 2020, at the population estimates program, its population was 1,761. The Lafayette Parish portion of Duson is part of the Lafayette metropolitan statistical area, while the Acadia Parish portion is part of the Crowley micropolitan statistical area.