The Millennium Biltmore Hotel, originally named the Los Angeles Biltmore Hotel of the Biltmore Hotels group, is a luxury hotel located across the street from Pershing Square in Downtown Los Angeles, California, US. Upon its grand opening in 1923, the Los Angeles Biltmore was the largest hotel west of Chicago, Illinois in the United States. In 1969 the Biltmore Hotel was designated a Los Angeles Historic-Cultural Monument by the City of Los Angeles.