Woodruff is an unincorporated community in Navajo County, Arizona, United States. Woodruff is 10.5 miles southeast of Holbrook. Woodruff has a post office with ZIP code 85942. Woodruff was settled in 1876 by a group of members of the Church of Jesus Christ of Latter-day Saints led by Nathan Tenney and including Tenney's son Ammon M. Tenney. It was initially called Tenney's Settlement. In 1878 Lorenzo H. Hatch became the head of the LDS branch there.