Cumberland County is a county in the U.S. state of Maine. As of the 2020 census, the population was 303,069, making it the most populous county in Maine. Its county seat is Portland. Cumberland County was founded in 1760 from a portion of York County, Province of Massachusetts Bay, and named for William, Duke of Cumberland, a son of King George II. Cumberland County has the deepest and second-largest body of water in the state, Sebago Lake, which supplies tap water to most of the county.