Moss Bluff is a census-designated place in Calcasieu Parish, Louisiana, United States. The population was 12,522 at the 2020 census. Located just north of the city of Lake Charles, it is considered a suburb of that city. Moss Bluff is a burgeoning community, and is one of the communities in Calcasieu Parish besides Lake Charles and Sulphur experiencing growth. Several efforts have been made to incorporate Moss Bluff, but at the present time the community is unincorporated.