North Wilkesboro is a town in Wilkes County, North Carolina, United States. The population was approximately 4,116 at the 2000 census and is now 4,245 as of the 2010 census. North Wilkesboro is the birthplace and original home of Lowe's Home Improvement, which continues to have a major presence in the community. The town is also known as one of the birthplaces of the sport of stock-car racing, and the North Wilkesboro Speedway was the first NASCAR-sanctioned track.