Salvisa is a census-designated place in Mercer County, Kentucky, United States. Its population was 420 as of the 2010 census. Salvisa is located at the junction of U.S. Route 127 and Kentucky Route 1987, 10.7 miles north of Harrodsburg. Salvisa has a post office with ZIP code 40372, which opened on April 4, 1825.Salvisa was laid out in 1816.