Arkville is a hamlet in the Town of Middletown, Delaware County, New York, United States. It is located along New York State Route 28, one mile north of the village of Margaretville in the western Catskill Mountains. It has the ZIP code 12406. Arkville is built either on or very close to the site of an old Lenape village called Pakatagkan. The main office of the Catskill Center for Conservation and Development is located in the Erpf House along Route 28.