Ciudad del Este is the second-largest city in Paraguay and capital of the Alto Paraná Department, situated on the Paraná River. It is located 327 km east of Asunción, the capital, and is adjacent to the border with Brazil, to which it is connected by the Friendship Bridge on the Paraná River. It is the largest city within the Triple Frontier region, which borders Foz do Iguaçu, Brazil and Puerto Iguazú, Argentina.