Blissfield is a village in Lenawee County in the U.S. state of Michigan. The population was 3,277 at the 2020 census. The village is mostly located within Blissfield Township with only very small portions extending west into Palmyra Township and south into Riga Township. The Blissfield post office first opened March 28, 1828. Hervey Bliss, who was the first white settler in 1824 and for whom the town is named, was the first postmaster.