Perkasie is a borough in Bucks County, Pennsylvania, United States. Perkasie is 21.5 miles southeast of Allentown and 39.2 miles north of Philadelphia. Establishments in the borough early in the 20th century included silk mills, brickyards, lumber mills, tile works, a stone crusher, and manufacturers of cigars, tags and labels, and wire novelties. The population in 1900 was 1,803; in 1910, 2,779 people lived in Perkasie.