Johnstonebridge is a village in Dumfries and Galloway, Scotland. It is roughly halfway between Moffat and Lockerbie, and lies on the A74 motorway. The Annandale Water Services on the motorway are in Johnstonebridge; prior to the construction of the motorway there were services on the old A74 road there, one to serve each direction of the road. As with most of Annandale, the area is largely devoted to farming.