Cadillac is a city in and county seat of Wexford County in the U.S. state of Michigan. The population was 10,371 at the 2020 census, making it the second most-populated city in the Northern Michigan region, after Traverse City. Cadillac was settled as early as 1871 and formerly known as the village of Clam Lake before incorporating as a city in 1877. The city is located upon the shores of Lake Cadillac, connected by the Clam Lake Canal to Lake Mitchell.