Salisbury-Ocean City: Wicomico Regional Airport, or, more succinctly Salisbury Regional Airport, is located in unincorporated Wicomico County, Maryland, 5 miles southeast from downtown Salisbury, Maryland, United States. Salisbury is the largest metropolitan area of Maryland's Eastern Shore with a population of 405,803 in the metropolitan statistical area, and is centrally located on the Delmarva Peninsula.