Two Harbors, colloquially known as "The Isthmus", is a small unincorporated community island village on the island of Santa Catalina Island, California, United States, with a population of 298. It is the second center of population on the island, besides the city of Avalon. It is mainly a resort village. It has only one restaurant, one hotel and one general store. The village has about 150 permanent residents who live on the isthmus year-round.