Dos Rios is an unincorporated community in Mendocino County, California. It is located 7 miles east-northeast of Laytonville, at an elevation of 961 feet. Dos Rios's ZIP code, 95429, has a population of 70. The Dos Rios AVA is located in the area. The Two Rivers post office opened in 1912 and changed its name to Dos Rios in 1915. The name comes from the place's proximity to the confluence of the Middle Fork of the Eel River with the Eel River proper.