Kane is a borough in McKean County in the U.S. state of Pennsylvania, 94 miles east by southeast of Erie. It was founded in 1864 by Civil War General Thomas L. Kane of the famous Bucktail Regiment at an elevated site 2210 feet above sea level. In the early part of the 20th century, Kane had large glass works, bottle works, lumber mills, and manufactures of brush handles, saws, cutlery, screen doors and windows. The population peaked in the 1920s but has since declined to 3,612 people in 2020.