Wayne is a county in the Commonwealth of Pennsylvania. It is part of Northeastern Pennsylvania. The county's population was 51,155 at the 2020 census. The county seat is the Borough of Honesdale. The county was formed from part of Northampton County on March 21, 1798, and was named for the Revolutionary War General Anthony Wayne. The Lehigh River, a 109-mile-long tributary of the Delaware River, rises in southern Wayne County.