Wheeler Lake is located in the northern part of the state of Alabama in the United States, between Rogersville and Huntsville. Created by Wheeler Dam along the Tennessee River, it stretches 60 miles from Wheeler Dam to Guntersville Dam. It is Alabama's second largest lake at 68,300 acres, and only a few hundred acres smaller than the largest lake in Alabama, Guntersville Lake, which is 69,100 acres and is separated by the Guntersville dam from the lake.