The Ysyk-Köl Region is one of the regions of Kyrgyzstan. Its capital is Karakol. It is surrounded by Almaty Region, Kazakhstan to the north, Chüy Region to the west, Naryn Region to the southwest, and Xinjiang, China to the southeast. It takes its name from Lake Issyk-Kul, the world's second-largest high altitude lake. Its total area is 43,735 km2. The resident population of the region was 501,933 as of January 2021. The region has a sizeable Russian minority.