Qashqadaryo Region is one of the regions of Uzbekistan, located in the south-eastern part of the country in the basin of the river Qashqadaryo and on the western slopes of the Pamir-Alay mountains. It borders with Tajikistan, Turkmenistan, Samarqand Region, Bukhara Region and Surxondaryo Region. It covers an area of 28,570 km2. The population is an estimated 3,408,345, with 57% living in rural areas. The regional capital is Qarshi.
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