Loxley is a city in Baldwin County, Alabama, United States. As of the 2010 census, the population of the town was 1,632. It is part of the Daphne-Fairhope-Foley metropolitan area. Loxley is becoming a popular location for the expansion of the suburbs from Daphne and Spanish Fort, Alabama, because it is served by an Interstate 10 exit and is almost directly between the cities of Mobile, Alabama, and Pensacola, Florida.