Larkana is a city located in the Sindh province of Pakistan. It is the 15th largest city of Pakistan by population. It is home to the Indus Valley civilization site Mohenjo-daro. The historic Indus River flows in east and south of the city. The city is located within Larkana District. Formerly known as "Chandka", Larkana is located on the south bank of the Ghar canal, about 40 miles south of the town Shikarpur, and 36 miles northeast of Mehar.