Middleton Grange is a suburb of Sydney, in the state of New South Wales, Australia. Middleton Grange is located 40 kilometres west of the Sydney central business district, in the local government area of the City of Liverpool and is part of the Greater Western Sydney region. Middleton Grange consists of approx 2550 lots with provision made by Council. Major land developers are now developing and selling housing blocks, along with some smaller land individual holders/farmers.