Hortolândia is a Brazilian municipality in the interior of the state of São Paulo. It is part of the Metropolitan Region of Campinas and the Mesoregion and Microregion of Campinas. It is located northwest of the state capital, about 110 km away. It is part of the São Paulo macrometropolis, which exceeds 29 million inhabitants and makes up approximately 75 percent of the state's population. The metropolitan regions of Campinas and São Paulo form the first megalopolis in the southern hemisphere.